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新城疫病毒W系疫苗抗小鼠移植瘤作用的实验研究 被引量:8

A EXPERIMENT STUDY ON IMMUNOTHERAPY OF XENOGRAFT TUMOR IN MICE BY NEWCAS-TLE DISEASE VIRUS ⅣSTRAIN VACCINE
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摘要 用新城疫病毒Ⅳ系疫苗免疫治疗小鼠腹水型肝癌移植瘤,结果:治疗组平均瘤重明显小于对照组(P<0.05);治疗组淋巴细胞应答水平显著高于对照组(P<0.05)。表明新城疫病毒Ⅳ系疫苗具有抗移值瘤作用。 Subcutaneous cancer cell xenografted mice were treated with Newcastle diseasevirus(NDV) vaccine.Results:The average tumor weight of the immunotherapy groups was re-markably less than the control group(P< 0.05). The lymphacyte response rate of theimmunotherapy groups was significantly higher than the control group(P< 0.05) The resultsindicate that live NDV Ⅳ strain vaccine may effectively inhibit the growth of liver cancerxenograft in mice.
出处 《广西医科大学学报》 CAS 1995年第2期197-201,共5页 Journal of Guangxi Medical University
关键词 新城疫病毒 IV系疫苗 免疫疗法 肿瘤 NDV Ⅳ Strain vaccine immunotherapy lymphacyte response
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