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乙肝和肝癌患者血清中肝细胞刺激物质的测定研究

DETERMINATION OF HUMAN HEPATOCYTESTIMULATOR SUBTANCE(HSS) IN SERA OFHEPATITIS B AND LIVERCANCER PATIENTS
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摘要 应用ELISA法检测了乙肝及肝癌患者血清中的HSS水平。结果表明,正常人血清中HSS含量为78.4±41.8μg/L,急性肝炎组为365.0±412.4μg/L,慢性活动性肝炎组为457.3±862.2μg/L,肝硬化组为518.1±425.6μg/L,肝癌组为304.8±216.9μg/L。各类乙肝和肝癌患者血清中的HSS含量均较对照组显著升高,提示血清中HSS升高与肝细胞损害有关,HSS可能是一种抗肝细胞损伤因子。 The levels of HSS in the sera of hepatitis B patients and liver cancer patients were determined by ELISA technique. The mean values and standard deviations of HSS meas-ured in the respective group were as follows: ①normal group 78.4±41.8μg/L; ② acute hepatitis group 365±412.4μg/L; ③chronic active hepatitis group 457.3±862.2μg/L; ④ liver cirrhosis group 518.1±425.6μg/L; ⑤liver cancer group 304.8±216.9μg/L. The levels of HSS in the sera of the hepatitis B patients and liver cancer patients were significantly higher than those of the control group. The results suggest that the increase in HSS levels correlates with the severity of the hepatic injury. HSS may be an antihepatocyte injury factor.
作者 陈智平 秦雪
出处 《广西医科大学学报》 CAS 1995年第4期507-509,共3页 Journal of Guangxi Medical University
关键词 乙型肝炎 肝肿瘤 肝细胞 刺激物质 hepatitis B liver cancer Hepatocyte stimulator substance
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