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重组牛碱性成纤维细胞生长因子促进儿童Ⅱ度烧伤创面的愈合 被引量:9

Healing effect of bFGF on burn wound degree II of children
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摘要 目的:观察重组牛碱性成纤维细胞生长因子(bFGF)对儿童II度烧伤创面的治疗作用。方法:1997 ̄2004年我院烧伤科住院的II度烧伤病人共798例分成两组,治疗组399例用1%聚维酮碘、生理盐水清洗创面后,用喷有bFGF的纱布外敷创面,用药剂量为150Au/cm2。对照组399例除bFGF不用外,其余治疗相同。观察创面完全愈合时间。结果:治疗组创面愈合时间较对照组创面愈合时间提前,浅II度创面平均提前3.68d,深II度创面平均提前5.02d,与对照组比较有显著性差异。结论:bFGF有明显促进儿童II度烧伤创面愈合的作用。 Objective: To observe the healing effect of bFGF (recombinant bovine basic fibroblast growth factor) on bum wound degree Ⅱ of children. Methods: 798 inpatiences from 1997 to 2004 were divided into two groups. One was experiment group. The other was control group .Bum wounds of expriment group were cleaned with 1% povidone iodine solution and NS, then they were treated with bFGF at a dosage of 150 Au/cm^2. Burn wounds of control group were cleaned with 1% povidone iodine solution and NS only. The time for complete healing (day) was observed after treatment. Results: The time for complete healing of exprintent group after treatment was less than the time of contral group ,The average ahead time (day) of superficial degree Ⅱ burn woand was 3,68 days .The average ahead time (day) of deep degree Ⅱ burn wound was 5.02 days. Conclusion: bFGF promotes the healing of burn wound degree Ⅱ of children significantly.
作者 刘燕 傅跃先
出处 《儿科药学杂志》 CAS 2005年第4期20-21,共2页 Journal of Pediatric Pharmacy
关键词 重组牛碱性成纤维细胞生长因子 烧伤创面 愈合 Recombinant bovine basic fibroblast growth factor, Burn wound Healing
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