摘要
[目的]探讨柴胡桂枝汤(CHGZT)改善溃疡愈合质量(QUH)的作用机制。[方法]对比观察大鼠乙酸胃溃疡形成后3个时间段再生黏膜表层黏液的分泌状态及CHGZT对其的影响。[结果]各组、各期再生黏膜黏液的分泌,不论是表层或黏膜内黏液,均较正常旺盛;与模型对照组相比,CHGZT5d、30d再生黏膜表层黏液均明显增厚(P<0.01)。[结论]增加再生黏膜表层黏液分泌可能是CHGZT改善QUH的作用机制之一。
[Objective]To probe into the mechanism of Chaihu Guizhi decoction （CGD） in improving the quality of ulcer healing （QUH）. [Methods] The secretion of surface layer mucus from regenerative mucosa during three periods was observed after gastric ulcer＇s formation by acetic acid in rats, and the influence of CGD on which was investigated. [Results] The mucus secretion of regenerative mucosa from surface layer or mucosa in every guoup and each period was more exuberant than that of normal group. The surface layer mucus from regenerative mucosa after 5 days and 30 days in CGD group was more than that of model group（P〈0. 01）. [Conclusion] Increasing surface layer mucus secretion of regenerative mucosa was perhaps one of the mechanisms of CGD in improving QUH.
出处
《中国中西医结合消化杂志》
CAS
2005年第4期243-245,共3页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
基金
湖北省卫生厅基金资助项目(30224801)
关键词
柴胡桂枝汤
溃疡愈合质量
胃黏液
Chaihu Guizhi decoction （CGD）
quality of ulcer healing
gastric mucus
