摘要
目的分析小梁切除术对青光眼患者角膜内皮细胞的影响及相关因素。方法358例(399只眼)青光眼病例小梁切除术治疗前及治疗后1个月行角膜内皮细胞检查,观察形状和数量的变化。结果小梁切除术未发生浅前房者,周边角膜内皮细胞丢失率为4.5%,中央角膜内皮细胞丢失率为3.0%(P>0.05)。Ⅰ度浅前房,周边丢失率为7.1%,中央丢失率为5.9%(P>0.05)。Ⅱ度浅前房,周边丢失率为9.1%,中央丢失率为6.5%(P>0.05),差异均无显著性。Ⅲ度浅前房,周边丢失率为54.7%,中央丢失率为45.2%(P<0.01),差异有显著性。结论青光眼小梁切除术可以造成角膜内皮细胞的损害。而浅前房是其损害的重要原因,尤其是Ⅲ度浅前房。
OBJECTIVE To probe the effect of glaucoma filtering surgery on corneal endothelial cell density and relative factors. METHODS Change of corneal endothelial cell shape and quantity were examinedbefore operative and at 1 month after operation in three hundred and fifty-eight patients （399 eyes） with glaucoma.RESULTS Cell loss rate was 4.5% at brink of cornea, and was 3.0% at center of cornea in the normal anterior chamber group （P〉 0.05） Cell loss rate was 7.1% at brink of cornea and 5.9% at center of cornea （ P 〉0.05） in one degree of shallow anterior chamber group （P〉0.05） . Cell loss rate was 9.1% at brink of cornea and 6.5% center of cornea in 2 degree of shallow chamber group （P〉0.05） .Cell loss rate was 54.7% at brink of cornea and 45.2% at center of cornea in 3degree shallow group （P〈0.01） . There is significant statistical difference between the 3 degree shallow group. CONCLUSIONS Glaucoma filtering surgery can affect corneal endothelial cell density. The primary reason is shallow anterior chamber after operation, especially three degree shallow anterior chamber.
出处
《中国中医眼科杂志》
2005年第3期138-139,共2页
China Journal of Chinese Ophthalmology
关键词
青光眼
小梁切除手术
角膜内皮细胞
浅前房
glaucoma
filtering surgery
corneal endothelial cell
shallow anterior chamber
