摘要
目的:观察SARS患者血清白介素-6(IL-6)含量变化。方法:用放射免疫法检测29例SARS患者血清白介素含量,与正常对照组比较。结果:进展期SARS组患者血清IL-6含量高于正常的百分率为18/29(62.1%),低于正常的百分率为3/29(10.3%)。发病后21天和病后2.5个月SARS组患者中血清IL-6含量高于正常的百分率分别为10/29(34.4%)和4/29(13.7%)。低于正常的百分率分别为3/29(10.3%)和2/29(6.9%)。重型SARS组患者进展期与发病21天后血清IL-6含量明显高于普通型SARS组。结论:SARS患者存在免疫反应异常,血清白细胞介素-6含量变化可能是SARS发病机制中一个环节。
Objective： To observe the serum lnterleukin- 6（IL- 6） in patients with .Severe Acute Respiretory Syndrome （SARS）. Methods： The serum lnterleukin - 6 was measured by RIA. and compare with those controls. Results： The results showed that the percentage of elevation of serum IL - 6 in patients with SARS was 62.1% and the percentage of depression was 10.3%, in progressive stage. The percentage of elevation of serum IL - 6 in patients with SARS were 34.4% and 13.7% respectively, the percentage of depression were 10.3% and 6.9% respectively after 21 days and after 2.5 months, serum IL- 6 in severe type of patients was significantly higher than those in general patients in progressive stage and after 21 days. Conclusion：There was immunoreaction abnormity in patients with SARS, The change of Interleukin - 6 in patients with SARS may be a tacheon pathogeny.
出处
《华西医学》
CAS
2005年第3期482-483,共2页
West China Medical Journal
