摘要
目的总结重型肝炎病人肝移植围手术期若干问题处理的经验。方法对我院2002年1月至2004年2月完成的48例重型肝炎病人的围手术期处理进行回顾性分析。结果本组48例重型肝炎病人肝移植后存活40例(83.3%,存活1个月至2年),其中31例出现急性肾功能衰竭,22例出现肝移植相关性脑病,19例并发严重肺部感染。术前合并严重感染、严重肺动脉高压、肾功能衰竭或APACHEⅡ评分>20分者,肝移植后死亡风险较大。结论术前评估及适当调理和有效的围手术期处理是提高重型肝炎病人肝移植成功率的关键。
Objective 1o evaluate and summarize the experience in perioperative management oforthotopic liver transplantation （OLT） in patients with fulminant hepatitis. Methods The clinical data of 48 patients undergoing OLT in our hospital from January 2002 to February 2004 were retrospectively analyzed. Results The survival rate of the recipients who achieved long term survival of 1 month - 2 years was 83.3%（40/48）. Complications including OLT-related acute renal failure in 31cases, OL-related encephalopathy in 22 and severe pulmonary infection in 19 appeared after the operation. There were higher risks of death in recipients with uncontrolled preoperative pulmonary infection, high pressure of pulmonary artery, renal failure and high APACHE Ⅱ score （〉20）. Conclusions Preoperative evaluation, proper regulation and effective perioperative management are important for improving survival rate of the patients with fulminant hepatitis after OLT.
出处
《中华肝胆外科杂志》
CAS
CSCD
2005年第7期446-448,共3页
Chinese Journal of Hepatobiliary Surgery
关键词
重型肝炎
肝移植
围手术期
肺动脉高压
肾功能衰竭
Liver transplantation
Fulminant hepatitis
Perioperative management
Complication
