摘要
目的:研究竹叶椒片对大肠杆菌所致大鼠慢性盆腔炎的治疗作用。方法:采用大肠杆菌O-B4标准菌株的菌液注入大鼠子宫内,制备大鼠慢性盆腔炎动物模型。大鼠分6组:假手术组、模型组、竹叶椒大、中、小剂量组和妇科千金片组,分别给予相应药物,每天ig 2次,连续21 d。然后测定大鼠免疫功能并进行大鼠子宫组织形态学观察。结果:给药组大鼠血清凝集素效价显著升高,淋巴细胞转化指数也明显提高,组织形态学观察发现给药组大鼠慢性盆腔炎病理改变明显减轻。结论:竹叶椒片对大肠杆菌所致大鼠慢性盆腔炎有明显治疗作用。
AIM： To investigate the therapeutic effects of Zhuyejiao tablets （Tab. ZYJ） on chronic pelvic inflammation （CPI） induced by coliform in rats. METH-ODS： The CPI model was made by injecting coliform O-B4 standard strains in the uterus of rat. Animals were randomly divided into six groups and drugs were administered for 21 days, bid, respectively. The immune function of animals was measured and the uterus was pathologically observed. RESULTS： The level of serum agglutinin and lymphocyte transformation index markedly increased in all ZYJ groups. Morphological investigation also revealed the alleviation of inflammation in ZYJ groups. CONCLUTION： ZYJ has therapeutic effects on chronic pelvic inflammation in rats.
出处
《中国临床药理学与治疗学》
CAS
CSCD
2005年第7期804-807,共4页
Chinese Journal of Clinical Pharmacology and Therapeutics
