摘要
目的了解葡萄球菌的临床分布和耐药特性,为临床合理使用抗感染药物提供依据。方法回顾性调查320株葡萄球菌对13种抗感染药物的耐药性。结果320株葡萄球菌中,金黄色葡萄球菌48株、表皮葡萄球菌121株、溶血葡萄球菌114株,甲氧西林耐药率分别为29.2%、73.6%、和67.5%;万古霉素、呋喃妥因、复方磺胺对葡萄球菌具有较强的抗菌活性。结论凝固酶阴性葡萄球菌是临床主要病原菌,而且对常用抗感染药物比金黄色葡萄球菌更具耐药性,耐甲氧西林葡萄球菌的耐药性比甲氧西林敏感葡萄球菌明显增强。
Objective To find out the clinical distribution and drug-resistance character of staphylococci for using anti-infective drug reasonably. Method 320 strains of Staphylococcus were reviewed for resisting to 13 anti-infective drugs. Results Among 320 strains of Staphylococci, there ware 48 strains of Staphylococcus auresu, 121 strains of Staphylococcus epidermidis and 114 strains of Staphylococcus haemolyticus. Their rates of resisting to methicillin ware 29.2%,73.6% and 67.5% respectively. The vancomycin, nitrofurantion and trimethoprim/sulfa showed strong antibacterial activity. Conclusions Staphylococcus with coagulase-negative is the primary pathogenic bacteria in clinic, and their drug-resistance character is stronger than that of Staphylococcus auresu, The drug-resistance of Staphylococcus resisted to methcillin is stronger than that of Staphylococcus sensitized methicillin.
出处
《江西医学检验》
2005年第4期311-312,358,共3页
Jiangxi Journal of Medical Laboratory Sciences
关键词
葡萄球菌
耐药性
甲氧西林
Staphylococcus
Drug-resistance
Methicillin
