摘要
目的:探讨脑导纳环重搏波相(Ⅲ相)面积对高血压病患者的血管弹性判定的诊断价值。方法:高血压组患者选自2002-12-26/2003-01-20宣武医院的高血压门诊的就诊患者23例。对照组健康者选自2002-10-21/12-26某大学在校学生和教工63例。两组受试者均知情同意。应用深圳市辉大高科技发展有限公司研制和生产的HD-ENG导纳式双侧脑血流图自动检测仪及相应软件对两组受试者进行脑导纳微分环检测。由检测仪采集的脑导纳血流图信号(ΔY),经微电脑自动微分后产生一阶导纳微分图(dy/dt)。以ΔY为X轴坐标,dy/dt为Y轴坐标,自动拟合成脑导纳微分环。脑导纳环图可分为4个相限,以X轴为基线,从起点始,环绕X轴时相依次定为Ⅰ,Ⅱ,Ⅲ,Ⅳ相。Ⅲ相:为重搏波相,即从Y轴向右侧形成的一个小环所包含的区域,该面积大小反映脑动脉血管弹性。观察两组受试者脑导纳微分环第三象限面积及与导纳微分环总面积之比,为避免数据偏态分布,取自然对数(ln)调整后数据。结果:23例高血压患者和63名健康者均进入结果分析。①ln(脑导纳微分环的Ⅲ相面积):高血压组左侧和右侧与对照组比较差别显著。(-0.5796±1.3730,-0.7027±1.4840比-1.7499±1.5325,-1.8828±1.4562,t=3.194,3.271,P<0.05)。②ln(脑导纳微分环的Ⅲ相面积/导纳微分环的总面积):高血压组左侧和右侧与对照组比较有显著差别(-0.3063±0.9780,-4.2510±1.0605比-0.9697±1.2519,-1.1907±1.3446,t=2.199,2.353,P<0.05)。结论:脑导纳微分环可以定量检测脑血管弹性能力,对高血压患者的血管弹性能力的判断具有一定价值。
AIM： To investigate the value of dicrotic phase area of brain admittance loop （phase Ⅲ） in the judgment of blood vessel elasticity in patients with hypertension. METHODS： Twenty-three hypertensive patients were selected from the hypertension outpatient clinic, Xuanwu Hospital from December 26, 2002 to January 20, 2003, and 63 healthy controls were from students and teachers of a university from October 21 to December 26, 2002. All the subjects were told and consent about our investigation. The HD-ENG admittance-typed automatic detector for bilateral rheoencephalogram （developed by Shenzhen Huida High-Tech Co., Ltd.） and other softwares were employed to detect differential admittance loop of brain in all the subjects. The collected brain admittance rheoencephalogram signal （Ay） produced a phase of admittance differentiation diagram （dy/dt） after differentiated by a micro-computer automatically. The differential admittance loop was simulated and synthesized automatically by using Ay as coordinate axis X and dy/dt as coordinate axis Y. The brain admittance loop could be divided into 4 phases： From the coordinate origin （0, 0）, the phases the surrounding the coordinate axis X were phase Ⅰ, Ⅱ, Ⅲ and IV by using the coordinate axis X as baseline. Phase Ⅲ was the dicrotic phase, i.e.,the area of the first loop expanding from the coordinate axis Y rightwards, which reflected the elasticity of brain arterial blood vessel. The ratio of phase Ⅲ area of differential admittance loop to the total area of differential admittance loop was detected in the two groups. To avoid the skewed distribution, the data were adjusted after calculating natural logarithm（In）. RESULTS： All the 23 hypertensive patients and 63 healthy controls were analyzed in the result. ①The In values of phase Ⅲ area of brain differential admittance loop in the left and right sides in the hypertension group was significantly different from those in the healthy control group [-0.579 6±1.373 0, -0.702 7±1.484 0 vs -1.749 9±1.532 5, -1.882 8±1.456 2, t=3.194, 3.271, P 〈 0.05]. ②The In values of the ratio of phase Ⅲ area of differential admittance loop to the total area of differential admittance loop in left and right sides in the hypertension group were significantly different from those in the healthy control group[-0.306 3±0.978 0, -4.251 0±1.060 5 vs -0.969 7±1.251 9, -1.190 7±1.344 6, t=2.199, 2.353, P〈 0.05]. CONCLUSION： Differential admittance loop can be used to detect the capacity of brain blood vessel elasticity quantitatively, so it plays a certain role in the judgment of capacity of blood vessel elasticity.
出处
《中国临床康复》
CSCD
北大核心
2005年第26期148-149,共2页
Chinese Journal of Clinical Rehabilitation
