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Three New Anthraquinones from Polygonum cillinerve 被引量:10

Three New Anthraquinones from Polygonum cillinerve
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摘要 Three new anthraquinones, emodin-8-β-D-(2"-O-coumarate)glucoside 1, emodin-8-β-D-(6'-O-acetyl)glucoside 2 and physicon-8-β-D-(6'-O-acetyl)glucoside 3, were isolated from the roots of Polygonum cillinerve and their structures were established by spectroscopic methods. The biological activity indicated that compound 1 had the scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals (the IC50 = 8.5 μmol/L), and compound 1-3 showed no activities against HL-60 and BCJC-823 cells by MTT method in vitro. Three new anthraquinones, emodin-8-β-D-(2"-O-coumarate)glucoside 1, emodin-8-β-D-(6'-O-acetyl)glucoside 2 and physicon-8-β-D-(6'-O-acetyl)glucoside 3, were isolated from the roots of Polygonum cillinerve and their structures were established by spectroscopic methods. The biological activity indicated that compound 1 had the scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals (the IC50 = 8.5 μmol/L), and compound 1-3 showed no activities against HL-60 and BCJC-823 cells by MTT method in vitro.
出处 《Chinese Chemical Letters》 SCIE CAS CSCD 2005年第8期1050-1052,共3页 中国化学快报(英文版)
关键词 Polygonum cillinerve ANTHRAQUINONE antioxidant activity cytotoxic activity. Polygonum cillinerve, anthraquinone, antioxidant activity, cytotoxic activity.
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  • 1State Administration of Traditional Chinese Medicine People's Republic of China, Zhong Hua Ben Cao, Shanghai science and technology press, 1999, Tomus, 2, p.650.
  • 2Agendae Academiae Sinicae Edita, Flora Reipublicae Popularis ~nicae, Science press, 1998,Tomus, 25(1), p.103.
  • 3J. P. Lee, B. S.Min, R. B. An, et al., Phytochemistry, 2003, 64(5), 759.
  • 4J. L. Li, A. Q. Wang, J. S. Li, et al., Chinese Traditional and Herbal Drugs, 2000, 31(5), 321.

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