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替米沙坦联合贝那普利治疗充血性心力衰竭的疗效观察 被引量:3

Efficacy of telmisartan combined with benazepril in patients with congestive heart failure
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摘要 目的:探讨替米沙坦联合贝那普利治疗慢性充血性心力衰竭(CHF)的临床疗效。方法:70例CHF 患者随机分成治疗组和对照组:治疗组给予替米沙坦80 mg/d,贝那普利10 mg/d,对照组给予贝那普利10 mg/d 及安慰剂治疗。两组基础治疗相同,疗程6个月。观察治疗前后两组患者的临床症状,超声心动图心功能指标,6 min 步行距离的变化。结果:两组治疗前、后相比左室射血分数(LVEF)、每搏量(SV)、心脏指数(CI)、6min 步行距离均有显著改善(P<0. 01) ,治疗组6 min 步行距离的改善优于对照组(P<0. 05) 。结论:替米沙坦联合贝那普利比单用贝那普利治疗CHF 可以取得更好的疗效。 Objective : To evaluate the clinical therapeutic efficacy of telmisartan combined with benazepril in patients with congestive heart failure (CHF). Methods : A total of 70 patients with CHF were randomly divided into treatment group (n= 38) and the CHF control group (n= 32). The clinical therapeutic efficacy and LVEF, SV, CI, 6 min walk trial and adverse reactions were analyzed. Results : The clinical therapeutic efficacy and LVEF, SV, CI, 6 rain walk trial in two groups were all significantly ameliorated after teatment (P〈0. 01) but the 6 rain walk trial were better in treatment group than that of CHF control group (P〈0. 05). Conclusion: Telmisartan combined with benazepril possesses more effects on treating patient with CHF compared with alone benazepril treatment.
出处 《心血管康复医学杂志》 CAS 2005年第4期355-356,共2页 Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词 替米沙坦 贝那普利 心力衰竭 充血性 Heart failure, congestive Telmisartan Benazepril
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