摘要
目的研究血浆D-二聚体、纤维蛋白原水平的联合测定在肺栓塞的诊断与治疗中的价值。方法对经临床确诊为肺栓塞患者测定其血浆D-二聚体与纤维蛋白原浓度。以正常人群为对照,并对结果进行t检验。结果肺栓塞患者血浆D-二聚体与纤维蛋白原浓度与对照组比较明显增高(P<0.01),经治疗后血浆D-二聚体与纤维蛋白原下降明显(P<0.01)。结论血浆D-二聚体与纤维蛋白原测定可作为诊断肺栓塞的首选筛选试验,并对肺栓塞疗效判定有一定的临床意义。
Objective To investigate the role of combined testing of plasma fibrinogen and D-dimer in pulmonary embolism patients. Methods The plasma fibrinogen and D-dimer in pulmonary embolism patients were measured. The differences between the patients and the normal individuals were studied by T test. Results The concentration of plasma fibrinogen and D-dimer were increased significantly in patients with pulmonary embolism group （P 〈 0.01 ） , and were decreased after treatment （P 〈0.01 ）. The difference was remarkable, especially in the patients with effective therapy （P 〈 0.01 ）. Conclusion Our primary result indicates that the changes of fibrinogen and D-dimer are important parameters for the judgment of the treatment efficacy of pulmonary embolism.
出处
《热带医学杂志》
CAS
2005年第5期609-611,共3页
Journal of Tropical Medicine
