摘要
目的:探讨妊娠期甲状腺自身抗体检测的临床意义。方法:30例甲状腺自身抗体阳性孕妇作为研究组,于妊娠15周内采集血、尿标本,放射免疫分析法测定血清TMAb和TGAb水平,化学发光免疫分析法测定血清FT3、FT4和TSH水平,砷-铈催化分光光度法测定尿碘水平,与60例该地区抗体阴性妊娠女性进行比较。结果:研究组血清FT3、FT4水平与对照组比较,差异有显著性(P<0.01);研究组血清TSH水平与对照组比较,差异有显著性(P<0.05);研究组孕妇尿碘水平中位数与对照组比较,差异有显著性(P<0.05)。结论:妊娠期进行甲状腺自身抗体检测具有重要的优生学价值。
Objective：To investigate the clinical value of measuring thyroid autoantibody in the gestation. Methods： The serum FT3,FT4 ,TSH,TMAb and TGAb levels of 30 thyroid autoantibody positive pregnant women as the study group were tested with chemiluminescent immunoassay and radiormmunoassay technique while the urine iodine levels were examined by spectro photometry. The results were compared with those of the control group who were 60 thyroid autoantibody negative pregnant women in the same area. Results：The serum mean FT3,FT4 levels in study group was significanty lower than those in control group （P〈0.01）. The serum mean TSH levels study group was significantly higher than those in control group （P〈0.05）. The median of urine iodine concentration in study group was signifcantly higher than that in control group. Conclusion：It has important eugenic value to measure thyroid autoantibody in the gestation.
出处
《临床医药实践》
2005年第8期566-568,共3页
Proceeding of Clinical Medicine
关键词
妊娠
甲状腺
自身抗体
pregnancy
thyroid
autoantibody
