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无创CPAP通气治疗慢性阻塞性肺疾病急性发作的临床研究

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摘要 目的探讨慢性阻塞性肺疾病(COPD)急性发作期无创机械通气的疗效.方法将转入ICU的COPD合并Ⅱ型呼吸衰竭的68例患者在抗感染、平喘、止痉、化痰等治疗的基础上,采用面罩机械通气,方式为持续气道正压通气(CPAP),每次通气2小时,每天4~6次.结果 68例患者,无创通气时间最短4天,最长9天,平均7.4天.通气前PaCO2(55.4±4.6)mmHg,PaCO2(78.7±12.3)mmHg.通气结束时PaO2(69.0±14.8)mmHg,PaCO2(54.2±6.3)mmHg.结论经面罩无创CPAP机械通气,可明显改善COPD急性发作期Ⅱ型呼吸衰竭患者的二氧化碳潴留及低氧血症,避免或减少遭受气管插管的痛苦或气管切开的创伤,减少院内感染发生的机会.
出处 《广州医药》 2005年第5期18-19,共2页 Guangzhou Medical Journal
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