期刊文献+

国产0.125%左旋布比卡因与0.2%罗哌卡因用于术后硬膜外镇痛效果比较

Effectiveness of 0.125% levobupivacaine and 0.2% ropivacaine in postoperative epidural analgesia: A comparative study
下载PDF
导出
摘要 目的:研究0.125%左旋布比卡因行病人硬膜外自控镇痛(PCEA)临床效果,并于0.2%罗哌卡因比较。方法:选择40例择期下腹部手术患者,ASA~级,采用随机双盲法分为两组:左旋布比卡因组(L组,n=20)、罗哌卡因组(R组,n=20)。两组术后分别采用0.125%左旋布比卡因、0.2%罗哌卡因复合小剂量吗啡(0.005%)和地塞米松10mg行病人自控硬膜外镇痛(PCEA),观察两组术后镇痛效果、运动阻滞程度和副作用的发生情况。结果:两组术后视觉模拟评分(VAS)、改良Bromage评分和病人自评镇痛效果满意度比较差异均无显著性(P>0.05)。两组不良反应发生率差异无显著性(P>0.05)。结论:0.125%左旋布比卡因复合小剂量吗啡和地塞米松用于病人术后硬膜外自控镇痛可取得和罗派卡因同样的镇痛效果。 Objective: To compare the clinical effectiveness of O. 125% levobupivacaine and 0. 2% ropivacaine in postoperative epidural analgesia. Method : Forty patients (ASA Ⅰ to Ⅱ ) scheduled for elective hypogastrium surgery were randomly dlvided into levobupivacaine and ropivacaine groups to receive postoperative cpidural analgesia: levobupivacaine group (L group) and ropivacaine group (R group). Low dose morphine and dexamethasone were added to both groups. The effectiveness of postoperative analgesia , degree of motor block and side--effects of two groups were observed. Result: There were no significant differencs in Visual pain scores (VAS), modified Bromage scale , patient satisfaction level and side- effects (P 〉 0.05 ). Conclusions: The effectiveness of 0. 125% levobupivacaine combined with low dose morphine and dexamethasone is satisfactory and reliable .
出处 《黑龙江医药科学》 2005年第4期27-28,共2页 Heilongjiang Medicine and Pharmacy
关键词 左旋布比卡因 罗哌卡因 术后硬膜外自控镇痛 levobupivacaine ropivacaine postoperative epidural analgesia
  • 相关文献

参考文献5

  • 1李荣胜,佘守章,周弘峰,谢晓青.0.2%左旋布比卡因与罗哌卡因持续硬膜外泵注镇痛效应的比较[J].中华麻醉学杂志,2004,24(1):73-75. 被引量:52
  • 2Vladimirov M , Nau C ,Mok WM , et al . Potency of bupivacaine stereoisomers tested in vitro and in vivo : biochemical , electrophysiological , and neurobehavioral studies[J].Anesthesiology , 2000 , 93(9):744~755
  • 3Casati A ,Santorsola R, Aldegher G, et al .Intraoperative epidural anesthesia and postoperative analgesia with levobupivacaine for major orthopedic surgery : A doubleblind, randomized comparison of racemic bupivacaine and ropivacaine[J]. J Clin Anesth, 2003, 15(2):126~131
  • 4Feldman HS, Covino BG . Comparative motor-blocking effects of bupivacaine and ropivacaine , a new amine amide local anesthetic , in the rat and dog[J]. Anesth Analg , 1998,67(6): 1047~1105
  • 5Murdoch JA , Dickson UK , Wilson PA , et al . The efficacy and safety of three concentrations of levobupivacaine administered as a continuous epidural infusion in patients undergoing orthopedic surgery[J]. Anesth Analy , 2002, 94(8):438~444

二级参考文献1

共引文献51

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部