摘要
目的探讨丝裂霉素C(MMC)预防浅表性膀胱癌等离子电切术(PKRBT)后复发的有效性。方法73例浅表性膀胱癌病人行PKBRT后即MMC 40 mg膀胱内灌注,常规MMC膀胱灌注12月。结果术后6月复发3例(4.1%),12月复发11例(15.1%),20月复发15例(20.5%)。结论MMC膀胱内灌注在PKRBT术后预防复发疗效良好。
Objective To evaluate the efficacy of intravesical instillation of mitomycin C after transurethral plasmakinetie resection for the prophylaxis of superficial bladder cancer recurrence. Method A total of 73 cases of superficial bladder cancer underwent transurethral plasmakinetic resection. All the cases were treated with intravesical instillation of 40 mg mitomycin C immediately after the operation. Regular intravesical instillation of mitomycin C has been given postoperatively to all cases for 1 year. All cases were followed up for 12 to 36 months （ the mean is 24.6 months）. Result There are 3,11 , 15 cases recurred at 6,12,20 months respectively. No serious side effect and complication developed either during or after instillation in all the cases. Conclusion lntravesical instillation of mitomycin C has been effective against recurrence of superficial bladder cancer after transurethral plasmakinetic resection,with advantages of good compliance and less systemic side effects.
出处
《广东药学》
2005年第4期72-73,共2页
Guangdong Pharmaceutical Journal
关键词
膀胱癌
丝裂霉素C
等离子电切术
bladder cancer
mitomycin C
plasmakinetic resection
