摘要
目的研究灵芝孢子油软胶囊对小鼠免疫功能的影响。方法分别以125、250、500mg/kgBW剂量的灵芝孢子油软胶囊给小鼠连续灌胃30～45d,测定各项免疫指标。结果灵芝孢子油软胶囊能促进小鼠的脾淋巴细胞增值、转化作用,促进小鼠的迟发型变态反应,提高小鼠的抗体生成细胞数、血清溶血素水平,促进小鼠的腹腔巨噬细胞的吞噬能力,显著提高小鼠的NK细胞活性。结论灵芝孢子油软胶囊具有增强免疫力功能作用。
Objective To study the impact of G. lucidum spores Softgel on the immune function of mice. Methods Seven experiments were carried out and 336 mice were used. 48 mice divided into 4 groups （Group Ⅰ, Group Ⅱ and Group Ⅲ and a control group ） each consisted 12 mice were used in each experiment, G. lucidum spores Softgel with the dose of 125mg, 250mg and 500mg were orally given to the mice in Group Ⅰ, Group Ⅱ and Group Ⅲ for a consecutive 30～45 days, while the mice in Group Ⅳ was only given maize oil. Results Proliferation nad trtansformation of spleen lympocytes, in the mice were increased, delayed anaphylactic reaction was intensified, the number of lymphocyte , B and the level of serum hemolysin also increased, the phagocytosis of pahcyte in abdominal cavity and the activity of NK cells enhanced , Conclusion G. lucidum spores Softgel can strengthen the immune function of mice .
出处
《中国热带医学》
CAS
2005年第6期1189-1191,共3页
China Tropical Medicine
