摘要
本文对六价铬化物（Ｋ２Ｃｒ２Ｏ７）的毒性进行了生物化学和病理学的研究。结果表明，大剂量六价铬化物可引起大鼠体重、血红蛋白浓度下降、血清丙氨酸转氨酶、碱性磷酸酶、乳酸脱氢酶活性和尿素氮增高，病理学观察，肝、肾组织细胞部分变性和坏死，而且还可诱发机体糖代谢紊乱，引起血糖升高，但对脂代谢无明显影响。
he biohemical and pathological changes caused by
toxicity of hexa-valent chromium compound were studied in rats。 The
high dosage ofhexavalent chromium compound caused a decrease of
weight and hemoglo-bin level and an increase of serum ALT,ALP LDH and
BUN, The patho-logical examination indicated that it brought about
the local denaturationand necrosis in the liver and kidney tissues,
and induced the increase ofserum glucose, but did not affect the
metabolism of lipids。
