摘要
将36例反复发作抑郁症病人随机分为A、B、C三组,分别服用175~200mg、125~150mg、75~100mg阿米替林维持治疗,进行3~4年的前瞻性、盲式、对照随访研究。结果显示:A组复发危险性比B组小153%,比C组小188%;4年缓解率A组为60.0%,B组为16.2%,C组为8.6%。提示充分治疗量仍是维持治疗的最佳剂量。
Thirty three cases with recurrent depression were randomly assigned to 3 groups, each taking one of the three different dosage of amitriptyline as maintenance treatment for the prevention of the relapse of depression. The follow-up periods were 3-4 years. The conclusion was: maintenance treatment with original adequate therapeutic dosage showed the best result in prevention of relapse.
出处
《上海精神医学》
1995年第1期11-13,16,共4页
Shanghai Archives of Psychiatry