摘要
本文对23例新生儿窒息及呼吸衰竭患儿采用高效液相色谱-电化学检测法测定去甲肾上腺素(NE)和肾上腺素(E),10例正常脐血为对照组,结果显示,窒息及呼衰缺氧可导致交感神经系统活性增强,分泌NE与E明显增多,急性期87.51±35.31pg/ml与恢复期38.55±21.77pg/ml比较差异非常显著(P<0.01),与脐血56.35±26.82pg/ml比较,P<0.05。随呼衰加重NE与E水平均增高,Ⅰ型61.44±33.48与Ⅱ型100.4±22.31(P<0.05)。NE与PO2呈负相关,r=-0.414,但无统计学差异。
Plasma catecholamine (noradrenaline and adrenaline) was determined in the neonatal asphyxia and respiratory failure of 23 cases by high performance liquid chromatography with electro chemical detecti9n (HPLC-ECD), Umbilical blood of 10 cases was controlled. The results showed: 1. Hypoxia of asphyxia and respiratory failure caused increase of sympathetic nervous system activity to secrets NE and E. Compared the value of acute stage (87. 51±35. 31pg/ml) with convalesent stage (38. 55±21. 77). between which there was considerable statistical difference (P<0. 01). 2. NE and E levels increased was aggravation of hypoxia.Value of Ⅰ type of RF was 61. 44±33. 44,Ⅱ type was 100. 4±22. 31 (P<0. 05). 3. NE and PO2 showed negative correlation (r= -0. 414) but there was on statistical difference.
出处
《新生儿科杂志》
1995年第3期110-112,共3页
The Journal of Neonatology