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正常人群痘苗病毒抗体的测定

Detection of antibody to vaccina virus in normal individuals
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摘要 用ELISA方法检测了155例不同年龄组正常人血清中的痘苗病毒IgG抗体。结果如下.12岁以下儿童全部为阴性,13岁以上各年龄组抗体阳性率为35.0%~80.O%,总阳性率为38.7%;在各阳性年龄组中,抗体效价分布在1:200~1:1600之间,几何平均效价为1:283,分布在1:269~1:295之间.用间接免疫荧光方法检测上述同样标本中的痘苗病毒IgG抗体,结果12岁以下儿童全部为阴性,与ELISA方法检测结果一致,13岁以上各年龄组抗体阳性率在15.0%~25.O%之间,总阳性率为12.9%.在各阳性年龄组中,抗体效价分布在1:10~1:40之间,几何平均效价为1:14,分布在1:13~1:17之间. The serum antibody(Ab)to vaccina virus in 155 normal individuals of differentage groups were measured by enzyme linked immunoabsorbent assay(ELISA ).The Abunder 12 years children were all negtive ,the positive rate of Ab vaired from 35.O% tO80.o% among the individuals over 13 years ,and the total positive rate of that was38.7%. Among the positive age groups,the titer of Ab distributed from 1 :200 to 1 :1600 ,geometric mean titer(GMT)was 1 :283 and varied from 1 :269 to 1 :295.The Abof the same samples were measured by indirect immunofluorescence. The Ab under 12 yearschildren were also negtive ,the positive rate of Ab vaired from 15.O% to 25.O% amongthe individuals over 13 years and the total positive rate of that was 12,9%. Among thepositive age groups,the titer of Ab distributed from 1:10 to 1 :40,GMT was 1 :14 andvaried from 1:13 to 1:17.
出处 《延边医学院学报》 CAS 1995年第1期23-25,共3页 Journal of Medical Science Yanbian University
关键词 抗体 病毒 痘苗病毒 流行病学 vaccina virus antibodies, viral epidemiology
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  • 1贾希瑜,病毒学报,1989年,5卷,312页

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