4Osborn BL,Sekut L,Corcoran M,Poortman C,Sturm B,Chen G,et al.Albutropin:a growth hormone-albumin fusion with improved pharmacokinetics and pharmacodynamics in rats and monkeys[J]. Eur J Pharmacol,2002;456:149-58
5Takada S,Kurokawa T,Misaki M,Taira K,Yamagata Y.A new animal model for evaluation of long-term growth rate over one month by rhGH/PLGA microcapsule formulations[J].J Pharm Pharmacol,2003;55:951-61
6Clark R,Olson K,Fuh G,Marian M,Mortensen D,Teshima G,et al.Long-acting growth hormones produced by conjugation with polyethylene glycol[J].J Biol Chem, 1996;271:21969-77
7Tsubery H,Mironchik M,Fridkin M,Shechter Y.Prolonging the action of protein and peptide drugs by a novel approach of reversible polyethylene glycol modification [J].J Biol Chem,2004;279:38118-24
