摘要
用不同有机溶剂重结晶制备了尼莫地平的两种晶型Ｈ和Ｌ，并通过红外光谱、Ｘ－射线粉末衍射、差热分析等方法得到证实。实验测定了尼莫地平两种晶型的溶解度曲线，并计算热力学数据。
Two different polymorphic forms of nimodipine were
found and prepared, and characterized by means of X-ray powder
diffraction ,DTA and IR,Equilibrium solubilities at 5 temperatures in
water were determined and thermodynamic parameters were calculated.
出处
《药学学报》
CAS
CSCD
北大核心
1995年第6期443-448,共6页
Acta Pharmaceutica Sinica
关键词
尼莫地平
多晶型
红外光谱
X-射线粉末衍射
Nimodipine
Polymorphism
X-ray powder
diffraction
IR
Differential thermal analysis
