6[1]Fabbrini G,Juncos J,Mouradian MM,et al.Levodopa ph armacokinetic mechanisms and motor fluctuations in Parkinson's disease[J].Ann Neurol,1987,21(4):370-6 .
7[4]Beck KD,Valverde J,Alexi T,et al.Mesencephalic dopaminergic neurons protect ed by GDNF from axotomy-induced degeneration in the adult brain[J]. Nat ure,1995 26,373(6512):339-41.
8[5]Hoffer BJ,Hoffman A,Bowenkamp K, et al.Glial cell line-derived neur otrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo [J].Neurosci Lett,1994,182(1):107-11.
9[8]John D E,Robert H R.Dopamine synthesis,uptake,metabolism,and recepto rs:rele vance to gene therapy of Parkinson's disease[J].Exp Neurol,1997,144(1):4-9.[ ZK)
10[10]Jiao S,Gurevich V,Wollf J A,et al.Long-term correction of rat mode l of Parkinson's disease by gene therapy[J]. Nature,1993,362(6419):450-453.