摘要
本研究以组化法观察电针对内毒素休克鼠肝脏的影响。结果表明内毒素休克鼠肝糖元几乎全部脱失，葡萄糖－6－磷酸酶（G－6－Pase），琥珀酸脱氨酶（SDH），5’－核苷酸酶（5’－Nase），镁激活的三磷酸腺苷（Mg++－ATPase）活性减弱，电针后糖元含量部分增加，SDH、Mg＋＋－ATPase和G－6－Pase活性较休克对照组增加。提示电计“人中”或“足三里”穴可能对改善肝脏代谢和提高膜的转运起一定的作用。
The expcrimental rats were randomly divided into three groups: L e. controI group; endotoxicshock group (the model of endotoxic shock was induced by intravenous administration of E. Coli endotoxin, 16mg/kg ): and electroacupuncture (EA ) group (' Renzhong' or ' Zusanli)' acupolnt wasstirnulated for 1o minutes at l hr after injection of endotoxin)- The experimental rats were decapitated at 75 minutes after injccting endotoxin. Their livers were taken out for cryostat section - and histo-chemical observation. The results were as follows: 1 ) The glycogen in the hepatic cells of endotoxicshocked rats were alrnost completely depleted- The activities of SDH Mg++u ATPase. G-6-Pase and5'~Nase were decreased: especially the activities of 5'-Nase 1n the biliary canallcull and sinusoids wereapparently rec1uced. 2 ) The content of hepatic glycogen in EA group was increased, but some of themwas still dePleted. The activities of SDH, Mg++-ATPase and G-6-Pase were slightly increased ascompared wlth that of the endotoxic shock group. The activity of 5'uNase was obviously increased afte r EA. The prelin1inary results indicated that EA at 'Renzhong' or IlZusanliI' acupoint of rats withndotoxic shock mlght play certain role on lmproving the hepatic metabolism and prornoting the rnembrane transport action
出处
《针刺研究》
CAS
CSCD
1995年第3期36-39,共4页
Acupuncture Research
基金
国家自然科学资金
