摘要
80名连续氟暴露5年以上的工人,按班组分为A、B两组;同样以非氟暴露工人20名为C组。A组42人口服拮氟锐复方剂,B组38人未服药,均不脱离生产岗位,进行为期一个月的现场试验观察。结果表明,与未服药对照组比较,服药组工人尿中氟及氟硼酸根含量及排出量明显增高,血清碱性磷酸酶活性下降,血清Zn、Cu含量增加,血红细胞免疫粘附能力明显增强。提示拮氟锐有较明显的预防氟损伤效应。
0 workers who had
continous exposure tofiuoride for 5 or more than 5years were dividedinto two groups:group A 42
workers and groupB38 workers,The workers in group A tookjiefurui,a mixture made of
boron,trace ele-ments,and chinese traditional herbs,for onemonth. Group B was sereved as
control.In addi-tion,group C of 20 workers was served as anunexposed control group.All workers
were ob-served for one month during exposure to flu-onide,The results showed that the
concentra-tions of urinary fluoride and tetrafluoroboratein workers of group A,as compared with
twocontrol groups,were significantly increased,thealkaline phosphatase activity reduced,the
con-tent of zinc,copperiron in serum increased,theability of red cell immune abherence was
en-hanced.It suggested that jiefurui might have aneffect of preventing fluoride damage.
出处
《中国工业医学杂志》
CAS
1995年第5期263-264,273,共3页
Chinese Journal of Industrial Medicine
基金
中国有色金属总公司"八五"项目
关键词
拮氟锐
抗氟作用
药理学
exposure to fluoride,jiefurui,antifluoride damage