摘要
研究香菇多糖注射液对３２例慢活肝患者外周血Ｔ淋巴细胞亚群和ＩＬ－２Ｒ表达的影响，其治疗前和治疗后的ＣＤ４￣＋分别是４０．１０±６．２２％和４５．８９±６；８０％，ＩＬ－２Ｒ分别是３８．８２±７．５９％和４９．１６±５．６４％，与治疗前比较，Ｐ＜０．０１。对照组１０例慢活肝，治疗前和治疗后ＣＤ４￣＋分别４３．９０％±７．７１％和４３．５％±９．８７％；ＩＬ－２Ｒ分别是４０．３０±９．３７％和４２．９５±７．５９％，与治疗前相比，Ｐ＞０．０５。香菇多糖注射液使慢活肝患者的外周血ＣＤ４￣＋细胞和ＩＬ－２Ｒ表达的增加，可能是香菇多糖对慢活肝外周血ＣＤ４￣＋有活化作用。其作用机制将进一步探讨。
The effects of ientinan on peripheral blood T lymophocytes and the expression of inter-leukin 2 receptor(IL-2R)in patients with chronic active hepatitis (CHA)was observed.In the treatments grotip,there are 32 cases with CAH, after theatment the the mean percentage ofCD4￣+and IL-2R was 45. 89±6. 80%aid49. 16±5. 64%compared with the data before treat-ment(CD4￣+ 40. 10±6. 22%and IL-2R 38. 82±7.59%),it shows statistical significance(P<0.01),10 cases with CAH in control group,after treatment the rnean percentage of CD4￣+ andIL-2R was 43. 50 ± 9. 87%and 42. 95 ± 7. 59%, compared with the data before treatmentCD4￣+ 43. 90±7. 71,IL-2R 40. 30±9. 37%),it shows on statistical significance(P>0.05),so ientinan has increased CD4￣+and the expression of IL-2R of patients with CAH. It may beassociated with activated effects of ientinan on CD4￣+ cell of patients with CAH,its mechanismwill be researched.
出处
《中国免疫学杂志》
CSCD
北大核心
1995年第5期298-299,302,共3页
Chinese Journal of Immunology
关键词
香菇多糖
T淋巴细胞亚群
白细胞介素2
受体
Ientinan T-lymphocyte Interleukin 2 receptor Chronic active hep-atitis
