摘要
本文对22例有排卵不孕妇女于 B 超监测排卵的同时,在卵泡中期、围排卵期和黄体中期测血清 LH、FSH、PRL、E_2、P、T;排卵后第10～14天取子宫内膜行病理学检查。按子宫内膜发育落后于月经周期>2天判断为黄体功能不全(LPD)。比较 LPD 组(n=12)和正常组(n=10)生殖激素值与卵泡直径的差异。结果;FSH 和卵泡期 LH、E_2在两组间无差异,黄体期 LH、E_2、P 水平,LPD 组低于正常组(P<0.05);而 PRL、T 水平,LPD 组均高于正常组(P<0.05)。正常组卵泡直径大于 LPD 组(P<0.05)。结果提示 LPD 的发生与高 PRL、高 T 及黄体期低 LH 有关;卵泡发育不成熟也是 LPD 的原因之一。
Serum LH,FSH,E_2,P,T,and PRL were measured during mid-follicular,periovulatory and middle luteal phase of the menstrual cycle,and B ultrasound were performed for detection of ovulation in 22 ovula- tory infertile women.Luteal phase defect(LPD)was definedas endometrial development being more than 2 days out of phase on biopsy.Comparison between the LPD group (n=12) and the normal group (n=10) showed no difference in terms of serum FSH,LH, and E_2 levels in follicular phase (P>0.05).However, in luteal phase,serum levels of LH,E_2,and P in LPD group were lower than in normal group(P<0.05 )whearas PRL and T levels in LPD were higher than in normal group(P<0.05),and the follicular size in LPD group was smaller(P<0.05).The results indi- cated that development of LPD was associated with high levels of PRL,T and low LH in the luteal phase.Abnormal follicuiogenesis may be another causitive factor for LPD.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
1995年第1期21-23,共3页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
黄体功能不全
生殖激素
卵泡直径
病理化学
Luteal phase defect
Progesterone Testosterone
Prolactin
Follicular size
