摘要
通过蹬车运动试验,观察36例常规尿蛋白检查阴性的糖尿病患者,运动前、后血、尿中β2微球蛋白(β2-MG)改变,结果17例Ⅰ型糖尿病患者蹬车后30分钟和60分钟尿β2-MG较蹬车前明显增加,19例亚型糖尿病患者蹬车运动后60分钟尿β2-MG增加,而对照组无一改变。对28例运动后尿β2-MG增加者,随诊5年后22例(78.6%)尿蛋白转为阳性,说明DM患者运动后β2-MG改变可能有助于糖尿病肾病的早期发现。
The changes of serum and urinary β2-microglobulin (β2-MG)before and after exercise testing by bicycle ergometers were observed on 36 cases of diabetic patients without urinary protein by routine test. 28 normal subjects matched in age and sex were taken as control. The results showed that the urinary β2-MG were significantly increased after exercise testing for 30min and 60min in 17 patients with IDDM and significantly increased in 19 patients with NIDDM after exercise testing for 60min,but no change in normal control. The urinary protein of 22 (78.6%)among 28 cases with increased urinary β2-MG after exercise testing became positive by routine test after followed for 5 years. These results indicated that urinary β2-MG increased after exercise testing may be helpful to the earlier detection of diabetic nephropathy.
出处
《中国糖尿病杂志》
CAS
CSCD
1995年第2期96-98,共3页
Chinese Journal of Diabetes
关键词
Β2-微球蛋白
糖尿病
血液
尿
运动
NIDDM Diabetic nephropathy IDDM β_2-microglobulin (β_2-MG)