摘要
从美国沼泽绿蛙的皮中分离、提取得到蛙皮活性提取物，体外抗菌试验表明，该活性提取物对金黄色葡萄球菌等有抑制作用。另外，小鼠分别ｐｏ０．２２ｇ／ｋｇ和０．４５ｇ／ｋｇ活性提取物，能明显降低致炎剂导致的小鼠耳肿胀率，分别比空白组降低１８．３％和３１．６％；能明显抑制小鼠血管通透性，Ａ５９０ｎｍ吸收值分别比空白组降低２３．４％和２４．３％。
The active substances were separated from hona guentheri skin(RGAE).RGAE decreased the ear swelling caused by xylene and peritoneal permeability ind uced by acetic acid in mice. With the doses of 0.22 and 0.45 g/kg by po administration,the swelling rate was reduced by 18.3 and 31.6% respectively and the abeorption at A590nm(represent poritoneal pormeability)was reduced by 23.4 and24.3%respectively as compared with control group.The antimicrobial activity of RGAE against 12 bacteria(in vitro)was also studied.
出处
《中国药科大学学报》
CAS
CSCD
北大核心
1995年第5期314-317,共4页
Journal of China Pharmaceutical University
关键词
沼泽绿蛙
蛙皮
活性提取物
抗菌
抗炎
Bana guentheri
Active extracts
Antimicrobial activity
Antinflammatory activity
