摘要
目的研究硒、钼、硼对氟中毒大鼠的氟斑牙发生的影响。方法 Wristar大鼠随机分为8组(雌雄各半):硒1组、硒2组、钼1组、钼2组、硼1组、硼2组、氟组、对照组。各组均喂以含Fˉ45mg/L的蒸馏水及含不同浓度微量元素的饲料,观察大鼠的一般情况,氟斑牙的发生。结果硒组体质量增加与对照组接近,优于钼组和硼组(P<0.05)。说明硒对动物的生长发育没有带来不利影响;实验结束时,硒组有3例无氟斑牙,与钼、硼组比较差异有显著意义(P<0.05),表明硒可能有效地阻止氟斑牙的发生。结论在实验设计剂量下,硒、钼、硼可能具有拮抗氟中毒的作用,而硒作用更好并减少了氟斑牙的发生。
Objective To study the effect of selenium,molybdenum,and boron on occurrence of dental fluorosis in rats with chronic fluorosis.Methods 64 Wistar rats were randomly divided into 8 groups(the number either female or male was same in each group):selenium 1 group,selenium 2 group,molybdenum 1 group,molybdenum 1 group,boron 1 group,boron 2 group,fluoride group,control group.Every group were drinking fluoride(F ˉ)45mg / L of distilled water except control group.The fluoride and control group were fed normal fodd...
出处
《贵州医药》
CAS
2011年第1期21-23,共3页
Guizhou Medical Journal
关键词
氟中毒
氟斑牙
硒
钼
硼
拮抗
Chronic fluorosis Dental fluorosis Selenium Molybdenum Boron Antagonistic
