摘要
目的:探讨大连地区结直肠癌患者的临床病理特征以及近年来的变化趋势。方法:回顾性分析2002年1月—2006年12月经手术病理证实的582例结直肠癌患者,分析其临床病理特征,包括发病年龄、病变部位和病理类型等。结果:60～69岁和70～79岁为结直肠癌高发年龄段(P<0.05);直肠是最常见的发病部位;腺癌是主要的病理类型,其中以中分化腺癌为主。随着年龄的增加,高分化腺癌的构成百分比呈明显上升趋势,低分化腺癌的构成百分比呈明显下降趋势(P<0.05),中分化腺癌的变化趋势不明显。结论:大连地区结直肠癌的高发年龄段为60～79岁。随着年龄的增加,结直肠癌的恶性程度有所下降。
Objective:To study the clinical characteristics of patients with colorectal cancer(CRC) and their variation trends in Dalian area.Methods:Five hundred and eighty two CRC patients confirmed by histopathological examination were enrolled in this study from Jan 2002 to Dec 2006.The clinical characteristics of all the patients including average age of onset,tumor location,histopathological types,etc.were retrospectively analyzed.Results:The average age of all the 582 patients was 66 years.Colorectal cancer often occurs in the patients aged from 60-69 and 70-79 years(P<0.05).CRC commonly occurred in the rectum.The main pathological type was adenocarcinoma most of which was moderately differentiated.The proportion of highly differentiated adenocarcinoma tended to increase and that of poorly differentiated adenocarcinoma tended to decrease with the increase of age(P<0.05).However,there was no significant difference in the proportion of moderately differentiated adenocarcinoma.Conclusion:Colorectal cancer often occurs in the patients aged from 60 to 79 years.The degree of malignancy of colorectal cancer decreased with increase of age.
出处
《肿瘤》
CAS
CSCD
北大核心
2010年第11期969-972,共4页
Tumor
关键词
结直肠肿瘤
病理学
腺癌
Colorectal neoplasms
Pathology
Adenocarcinoma
