摘要
目的观察Eales病患者血浆内皮素-1(Endothelin-1,ET-1)水平,探讨其与Eales病的关系。方法将所有受试对象(包括Eales病患者及正常对照组)进行常规的全身检查及眼科检查,确定Eales病的分期,采用放射免疫法对ET-1进行测定。结果 Eales病组ET-1平均值高于正常对照组(P<0.05),差异有统计学意义;Eales病组新生血管前期组和新生血管期组ET-1平均值比较P>0.05,差异无统计学意义;Eales病组中男性ET-1平均值比女性平均值含量高(P<0.05),差异有统计学意义;Eales病组ET-1与年龄成正相关。结论 Eales病的发生可能与血浆内皮素的水平增高有关。
OBJECTIVE To observe Eales patients plasma Endothelin-1 level and explore the relationship between them.METHODS 1.Had all subjects(including Eales patients and normal matched control group) accept the conventional body checks and ophthalmic examination.2.FFA and ophthalmic examination results determined the stage of Eales disease.3.Radioimmunoassay used for Endothelin-1 tests.RESULTS 1.The average ET-1 of the patient group was higher than that of the control group(P<0.05).The difference was significant in statistical significance.2.The average ET-1 of the patient group was compared between the proliferative stage's and the non-proliferative stage's.The difference was statistically insignificant(P>0.05).3.The average ET-1 of the males'in the patient group was higher than that of the females'(P<0.05).The difference was significant in statistical significance.4.ET-1 was positively correlated with age in the patient group.CONCLUSIONS The increased level of plasma ET-1 was associated with the Eales disease.
出处
《中国中医眼科杂志》
2010年第6期326-328,共3页
China Journal of Chinese Ophthalmology
