摘要
目的 探讨早期血乳酸清除率对严重脓毒症与脓毒性休克患儿预后评估的价值.方法 选择2008年7月至2009年11月我院PICU收治的严重脓毒症、脓毒性休克32例患儿为研究对象,采用早期目标性液体复苏方案,测定复苏前后的动脉血乳酸水平,计算复苏6 h后血乳酸清除率,并与危重症评分作一致性分析,比较其与疾病预后的关系.结果 存活组液体复苏6 h后血乳酸清除率为(35±16)%,死亡组为(15±11)%,两组比较差异有统计学意义(P<0.01),在预后判断上乳酸清除率与危重症评分有较高的一致性(P>0.05).结论 早期乳酸清除率可作为判断严重脓毒症与脓毒性休克患儿预后的一个指标.
Objective To explore the value of early lactate clearance rate in outcome for severe sepsis and septic shock children. Methods Thirty-two children with severe sepsis and septic shock were selected in PICU from July 2008 to November 2009.Artery levels of lactate were measured before and after early goal-directed therapy,then calcuated the lactate clearance. Results Survivors group after 6 hours therapy showed a lower lactate learance (P＜0.01),no significant difference was found in nonsurvivors group [(35±16)% vs (15±11)%].There existed obvious correlation between lactate clearance and pediatric critical ilness score and PICS(P＞0.05). Conclusions Early lactate clearance could be regard as an indicator of outcome to severe sepsis and septic-shock children.
出处
《中国实用医刊》
2010年第20期21-22,共2页
Chinese Journal of Practical Medicine
