摘要
目的明确胫神经不同比例切断后与所支配肌肉肌力变化的关系,讨论其临床意义。方法正常SD大鼠24只,随机分成4组,每组6只,A组切断左侧80%胫神经,B组切断60%,C组切断40%,D组切断20%,另一侧留做对照。6周后取材测湿重,并测量小腿三头肌肌力变化。结果4组小腿三头肌均有不同程度萎缩,收缩力下降,有显著差异;A组肌力平均下降88.2%,B组下降54.2%,C组下降19.5%,D组下降4.7%。结论大鼠胫神经干切断比例40%以下,不会过多影响肌力。
Objective To study the changes of the muscle strength after the selective tibial neurotomy and the relationship between the changes and the quantities of neurotomy, and to discuss the clinical significances. Methods Twenty-four normal SD mouse were divided into 4 groups with 6 in each. In group A, the left tibia nerve were cut off by 80%. 60% in group B, 40% in group C, 20% in group D, with the right as the control side. After 6 weeks measure the strength of the crural triceps and the weight of them, Results In all the groups muscle weight and muscle strength decreased. 88.2% strength decreased on the average in group A, 54. 2% in group B, 19, 5% in group C, 4. 7% in group D. Conclusion It will not damage strength of the crural triceps to cut off below 40% tibial nerve in SD mouse.
出处
《中华外科杂志》
CAS
CSCD
北大核心
2005年第16期1095-1097,共3页
Chinese Journal of Surgery
