摘要
目的了解云南省怒江州独龙族ABO和Rh等血型分布情况。方法 215名独龙族人群经试管直接凝集法分别检测了ABO、Rh、MN、P血型,采用血型群体遗传学研究方法,进行表现型及基因频率分析。结果 (1)ABO血型表现型频率顺序O>B>A>AB,基因频率r>p>q,民族指数=0.73。(2)Rh血型表现型以CCDee、CcDee多见,Rh(D)阴性率较高,为3.72%。(3)MN血型基因频率m=0.767 4,n=0.232 5。(4)P血型基因频率P1=0.162,P2=0.838。结论云南省怒江州独龙族人群ABO、MN和P血型系统抗原分布状况与南方汉族人群血型抗原分布特征基本相符,但Rh(D)阴性率较高。
Objective To investigate the distribution of ABO,Rh etc blood group antigens of the Dulong nationality from the Nujiang state of Yunnan province.Methods 215 subjects from the Dulong nationality were enrolled into the investigation at random,and the distribution of ABO,Rh,MN and P blood group antigen and their gene frequency analyzed.Results(1) The frequency of ABO phenotype was as following: O>B>A>AB,and gene frequency r>q>p.Nationality index was equal to 0.73.(2) Among Rh phenotypes,CCDee and CcDee were common,and the frequency of Rh(D) negative is high,3.72%.(3) As for the frequency of MN gene,m was equal to 0.7674,and n 0.2325.(4) The frequencies of P1and P2 were 0.162 and 0.838 respectively.Conclusion Generally,the distribution of ABO,MN and P in the Dulong nationality from the Nujiang state of Yunnan province accords with the distributive characteristic of blood type antigens of southern Han nationality.Unusually,the frequency of Rh(D) negative is more high.
出处
《临床输血与检验》
CAS
2011年第3期197-199,共3页
Journal of Clinical Transfusion and Laboratory Medicine
基金
昆明市重点科技项目(No.06S115140)资助
关键词
独龙族
红细胞血型
RH(D)阴性
Dulong nationality Red cell blood groups Rh(D) negative
