摘要
目的:观察3种根尖倒充填材料对人牙周膜细胞生长及超微结构的影响,从而指导材料的选择。方法:用材料直接接触细胞并计数以及透射电镜观察细胞结构变化。结果:3种材料接触培养后细胞生长速度减缓,3种材料之间差异有显著意义,细胞内超微结构显示内质网,线粒体等细胞器及细胞核的结构均有改变。结论:本实验的3种根尖倒充填材料对牙周膜细胞均有毒性作用,其中光固化复合树脂和银汞合金毒性较强,而化学固化玻璃离子粘固剂毒性较弱,临床使用较好。
Objective： To evaluate the effects of three root -end filling materials on the proliferation and the ultra -structure of human periodontal ligament cell （HPDLC） . Methods： HPDLC were cultured with three materials directly. The number of cells was calculated and structure was observed by transmission electrical microscope （TEM）. Results： The proliferation rates of cells cultured with three root - end filling materials directly decreased. The numer of endoplasms decreased, and the structure of mitochondria and nuclei changed. Conclusions： From this experiment, all of the three rootend filling materials are cytotoxic to HPDLC, among which amalgam and light curing composite resins are stronger than GIC.
出处
《口腔医学研究》
CAS
CSCD
2005年第4期399-401,共3页
Journal of Oral Science Research
基金
江苏省南京医科大学科技发展基金资助(编号:NY02077)
关键词
根尖倒充填材料
人牙周膜细胞
超微结构
Root -end filling materials Human Periodontal Ligament Cell Ultra- structure
