摘要
目的:探讨卵巢癌患者血清标志物CA125和临床病理之间的关系,为CA125在卵巢癌临床诊断、治疗、预后判断提供参考。方法:采用电化学发光免疫测定法检测82例卵巢癌患者以及20例正常对照者血清CA125的浓度,结合术后病理资料,应用统计学方法对其进行分析。结果:卵巢癌患者血清CA125浓度显著高于正常对照组(P<0.01);随着临床分期的增加,CA125浓度逐渐增加,期、期和期、期相比有统计学差异(P<0.01);血清CA125浓度和病理类型有关,浆液性囊腺癌显著高于非浆液性上皮性卵巢恶性肿瘤(P<0.05)。术后显示淋巴结转移为阳性者CA125浓度显著高于淋巴结转移为阴性者(P<0.05)。结论:并对卵巢癌诊断、鉴别诊断有一定意义,并对制定手术方案有一定指导意义。
Objective To explore the relationship between the level of CA125 in serum of patients with ovarian cancer and pathology,and to determine their clinical significance in diagnosis, treatment and prognosis of ovarian cancer. Methods Eighty-two patients with ovarian cancer and 20 healthy controls were measured their serum level of CA125 by means of ECLIA. Results The level of serum CA125 in patients with ovarian cancer was much higher than that in the healthy controls （P〈0.01）. The level of serum CA125 was related to pathology. The level of CA125 in patients with serous cystadenocarcinoma was much higher than that in the patients with non-serous cystadenocarcinoma（P〈0.05）. The level of serum CA125 in patients who had metastasis of lymph node was much higher
出处
《实用诊断与治疗杂志》
2005年第9期637-638,共2页
Journal of Practical Diagnosis and Therapy
