摘要
[目的]研究我国防晒化妆品中紫外线吸收剂的使用量。[方法]统计分析1996-2002年用反相高效液相色谱法测定的2 263份国产和进口防晒化妆品样品中常用的8种紫外线吸收剂的使用量。[结果]4-甲氧基肉桂酸-2- 乙基己酯、4一二甲氨基苯甲酸-2-乙基己酯、水杨酸-2-乙基己酯、3-(4’-甲基亚苄基)-d-I-樟脑、羟苯甲酮、2-苯基苯并咪唑-5-磺酸、1-(4-特丁基苯基)-3-(4-甲氧基苯基)丙烷-1,3-二酮、2-羟基-4-甲氧基二苯甲酮-5-磺酸在防晒化妆品中使用量总体均值分别为(41.5±24.6)mg/g、(41.2±25.2)mg/g、(33.5±16.7)mg/g、(20.4±12.2)mg/g、(20.1±13.8)mg/g、(19.6±10.1)mg/g、(13.8±8.8)mg/g、(11.1±16.1)mg/g,使用量均值年度变化(RSD)分别为6.65%、20.16%、16.56%、17.17%、10.17%、30.53%、14.65%、63.72%。[结论]使用量最大和年度使用量均值变化最小的紫外线吸收剂皆为4-甲氧基肉桂酸-2-乙基己酯,且都在我国规定的限量以内。
[ Objective ] To investigate the used amount of ultra-violet absorbents in sunscreen cosmetics in China. [ Methods ] Statistic analysis was conducted on the used amount of eight kinds of ultra-violet absorbents that were determined by RP-HPLC in 2263 sunscreen cosmetics from 1996 to 2002. [ Results ] For 2-ethylhexyl-4- methoxycinnamate, 2-ethylhexyl-4-dimethyl-aminobenzoate, 2-ethylhexyl salicylate, 3-( 4′-methylbenzylidene )-d-1-camphor, oxybenzone, 2-phenylhenzimidazole-5-sulphonic acid, 1- ( 4-tert-hutylphenyl ) -3- ( 4-methoxyphenyl ) propane-1, 3-dione and 2-hydroxy-4-methoxyhenzo-phenone-5-sulphonic acid in sunscreen cosmetics from 1996 to 2002, the used mean amount were ( 41.5 ± 24.6 ) mg/g, ( 41.2 ± 25.2 ) mg/g, ( 33.5 ± 16.7 ) mg/g, ( 20.4 ± 12.2 ) mg/g, ( 20.1±13.8 ) mg/g, ( 19.6±10.1 ) mg/g, ( 13.8±8.8 ) mg/g, ( 11.1±16.1 ) mg/g, respectively, and the annual variation of used mean amount( RSD ) was 6.65 %, 20.16 %, 16.56 %, 17.17 %, 10.17 %, 30.53 %, 14.65 %, 63.72 %, respectively. [ Conclusion ] The ultra-violet absorbent of the used maximum amount and the minimum annual variation of used mean amount is 2-ethylhexyl-4-methoxycinnamate.
出处
《环境与职业医学》
CAS
北大核心
2005年第4期348-350,共3页
Journal of Environmental and Occupational Medicine
关键词
紫外线吸收剂
防晒化妆品
使用量
ultra-violet absorbent
sunscreen cosmetic
used amount