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卡维地洛对早期肝硬化门静脉高压患者血液动力学的影响

Effect of Carvedilol on Hemodynamic Response in Patients with Cirrhosis and Portal Hypertension
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摘要 目的:观察卡维地洛对早期肝硬化门静脉高压患者血液动力学的影响。方法:治疗组口服卡维地洛8周,对照组不针对门静脉高压治疗,其它治则两组同。于治疗前后分别使用彩色多谱勒超声检测门静脉(PV)、脾静脉(SV)、胃左静脉(LGV)血液动力学参数,并统计分析。结果:治疗前两组各参数比较无统计意义(P>0.05)。治疗后,治疗组与对照组比较DPV、QPV、DSV、VSV、QSV、DLGV均有所下降,其中QPV下降2.50%,QSV下降33.83%。门静脉流速两组分别为16.60±3.12cm·min-1和16.58±3.13cm·min-1,无统计学意义(P>0.05)。结论:卡维地洛改善门静脉高动力状态同时降低门静脉阻力、门静脉压力,在早期肝硬化门静脉高压治疗中的作用值得进一步研究。
出处 《现代临床医学》 2005年第4期247-248,共2页 Journal of Modern Clinical Medicine
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