摘要
应用Koenigs-Knorr的原理化学合成熊果苷。该反应以葡萄糖和氢醌为原料,经乙酰化、溴代、缩合、脱乙酰基等反应制得熊果苷。该反应在常压下进行,原料易得,操作简单,适用于实验室小规模制备熊果苷。
Arbutin was synthesised from Hydroquinone and glucose by several steps of acetylation,bromization,condensation,deacetylation.The condensation complied with the principle of Koenigs-Knorr reaction.The reaction was run under atmosphere,raw materials were got easy.It is simple to operate and suitable for preparing Arbutin on a small scale in the laboratory.
出处
《香料香精化妆品》
CAS
2005年第4期11-12,27,共3页
Flavour Fragrance Cosmetics
基金
国家重大基础研究项目(2003CB761000)
