摘要
五氯酚作为杀虫剂、抗菌剂和防腐剂而被广泛使用,范围涉及工商业、农业、水产业及家居生活。五氯酚在沉积物和生物体内有富集作用,由于具有毒性高,持久性长及难降解等特点,其大量使用和不恰当处理,导致了土壤和水资源的污染,已成为一种不可忽视的环境污染物。在污染区的水体、土壤及动植物体内都能检测到一定水平的五氯酚。五氯酚可通过直接接触(皮肤和呼吸道)或食物链富集进入人体而对人体产生毒性及一系列不良影响。进入体内的五氯酚可长时间蓄积于肝、肾及脂肪组织中,对肝、肾产生毒性;使肿瘤发病率提高,干扰内分泌、影响免疫功能及阻碍生殖发育等。五氯酚不仅对人体有直接危害,而且可能在遗传学上具有潜在的危险性。
As a kind of pesticide, fungicide and preservative, PCP had been used extensively in industry, agriculture and domesticity throughout the world. PCP contamination is generally associated with sediments or soil, it can also concentrate in organism. Regarding the character of high toxicity, long persistence and difficult to degrade, PCP has become a kind of conspicuous environmental pollutant because of widely use and inappropriate disposal. In the contaminated area, PCP can be detected in the water, soil and the body of organisms. PCP can affect human health through directly exposure or through food chain. The absorbed PCP can be stored in liver, kidney and fat,it can also increase the incidence rate of tumork, disturb the endocrine system, affect immune function,inhibit reproduction and development. PCP not only has a direct impairment on human body but also shows a potential impact in genetics.
出处
《环境与健康杂志》
CAS
CSCD
北大核心
2005年第5期396-398,共3页
Journal of Environment and Health
基金
国家自然科学基金资助项目(20237010)
教育部高等学校骨干教师资助计划资助项目
关键词
环境污染物
氯酚类
内分泌系统
细胞凋亡
细胞毒性
Environmental pollutant
Chlorophenols
Endocrine system
Apoptosis
Cell toxicity
