摘要
目的探讨广西黑衣壮族人群的血压和血脂水平及其高血压与高脂血症的关系.方法采用整群抽样方法对1056例黑衣壮族人群的血压、身高、体重、体重指数、血脂及载脂蛋白(Apo)进行测定,并将其结果与925例当地的汉族人群作比较.结果黑衣壮族人群收缩压和脉压水平显著高于汉族人群(P<0.001),单纯收缩期高血压和高血压的患病率也明显高于汉族人群(P<0.001);而总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白-胆固醇和Apo B水平则显著低于汉族人群(P<0.05~0.001),高胆固醇血症和高脂血症患病率也显著低于汉族人群(P<0.05),但高密度脂蛋白胆固醇水平和Apo A1/B比值则显著高于汉族人群(P<0.001).黑衣壮族人群高血压患病率与TG呈显著正相关(r=0.425,P<0.05),而汉族人群高血压患病率则与TC呈显著正相关(r=0.623,P<0.001).结论黑衣壮族人群的血压和血脂水平与汉族人群存在显著差异,高血压和高脂血症患病率有密切关系.
Objective To investigate the levels of blood pressure and serum lipids, and examine the relationship between hypertension and hyperlipidemia in Hei Yi Zhuang Chinese living in Guangxi. Methods A total of 1056 people of Hei Yi Zhuang ethnicity were studied. Blood pressure, body height, body weight, and serum levels of lipids and apolipoprotein were measured. The data were compared with those in 925 people of Han ethnicity, who live in the same region. Results Systolic blood pressure and pulse pressure were significantly higher in Hei Yi Zhuang than Han Chinese (P 〈 0. 001 ). The prevalence of isolated systolic hypertension and hypertension was also significantly higher in Hei Yi Zhuang than Han Chinese (P 〈 0. 001 ). Serum concentrations of total cholesterol, triglycerides, low-density lipoprotein cholesterol, and apolipoprotein (Ape) B, and the prevalence of hypercholesterolemia and hyperlipidemia were significantly lower in Hei Yi Zhuang than Han Chinese ( P 〈 0. 05 ). Serum concentrations of highdensity lipoprotein cholesterol and the Apo A1 to Ape B ratio were significantly higher in Hei Yi Zhuang than Hart Chinese ( P 〈 0.001 ) . The prevalence of hypertension in Hei Yi Zhuang Chinese was positively associated with triglycerides (r = 0. 425, P 〈 0.05), whereas the prevalence of hypertension in Han Chinese was positively correlated with total cholesterol ( r = 0. 623, P 〈 0. 001 ). Conclusion The present study revealed a significant difference in blood pressure and serum lipids between Hei Yi Zhuang and Han ethnic groups, and an association between hypertension and hyperlipidemia.
出处
《中华心血管病杂志》
CAS
CSCD
北大核心
2005年第8期754-758,共5页
Chinese Journal of Cardiology
基金
国家自然科学基金资助(30360038)