摘要
目的探讨原发性心脏肿瘤(PCT)的发病学特点、病理组织学类型及临床病理特征。方法应用HE染色、组织化学法及免疫组化SP法对35例原发性心脏肿瘤进行病理形态学观察,并对其临床资料进行分析。结果根据形态学特点和免疫组化结果分析,35例中良性肿瘤33例,均为心脏黏液瘤;恶性肿瘤2例,1例为恶性纤维组织细胞瘤,1例为平滑肌肉瘤。结论原发性心脏肿瘤罕见,以青壮年多见,好发于心房;主要为良性肿瘤,以心脏黏液瘤最多见;原发性心脏恶性肿瘤更为罕见,但类型较多,形态结构复杂,免疫组化标记能够明确肿瘤的组织来源;有效的心脏外科手术切除肿瘤,对原发性心脏肿瘤的诊断、治疗和预后有十分重要的意义。
Objective To study pathogenic characteristics, histologic types and clinical pathologic features of primary cardiac tumors （PCT）. Methods Pathomorphology of 35 cases of PCT was observed with HE staining, histochemistry and immunohistochemistry, and their clinical data were analysesd. Results According to pathologic finding and immunohistchemical staining, primary cardiac tumors were 35 cases, in which 33 cases of benign tumor （cardiomyxoma） and 2 cases of malignant tumors （ malignant fibrous histocytoma and leiomyosarcoma, one each）. Conclusion PCT is rare. Most patients are in adolescent age, and most of the tumors are in the atrium. Primary cardiac malignant tumor （PCMT） is extremely rare. There are many types in PCMT, and their morphologic structures are complex. Immunohistochemical staining is able to find out the histogenesis of PCMT. It is very important for treatment and prognosis of PCT to make early and accurate diagnosis, and effective surgical procedures.
出处
《诊断病理学杂志》
CSCD
2005年第4期267-269,i0007,共4页
Chinese Journal of Diagnostic Pathology
关键词
心脏肿瘤
病理类型
免疫组织化学
Cardiac tumor
Pathologic types
Immunohistochemistry
