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奥氮平治疗老年期精神障碍100例临床分析 被引量:15

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摘要 目的评价奥氮平治疗老年期精神障碍的疗效和安全性.方法用奥氮平治疗老年期精神障碍100例,其中,老年期分裂症40例,阿尔采默病28例,脑血管病所致精神障碍26例,脑外伤所致精神障碍6例,疗程8周;采用简明精神病量表(BPRS)、阳性和阴性症状量表(PANSS)评价临床疗效,副反应量表(TESS)评价不良反应.结果 BPRS总分、PANSS总分、阳性症状量表评分治疗后1、2、4、8周末,阴性症状量表评分治疗后1、2、4、8周末与治疗前比较差异有显著性(P<0.05~0.01);奥氮平疗效显著,治愈率为72%,显效率为83%;常见的不良反应是体重增加.结论奥氮平对老年期精神障碍起效快,不良反应少,安全有效,服用方便,适合于住院及门诊老年期精神障碍者的治疗.
出处 《山东精神医学》 2005年第4期260-261,共2页 Shangdong Archives of Psychiatry
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