摘要
目的通过用不同的治疗剂量,来探讨90Sr敷贴治疗婴幼儿血管瘤的最佳方法以及限制最小的副作用。方法100例草莓状血管瘤、鲜红斑痣患儿,随机分为A、B两组,A组采用一次大剂量90Sr敷贴治疗,B组采用分次小剂量90Sr敷贴治疗。2个月后观察治疗效果以决定是否行第2次治疗。结果A组一次大剂量90Sr敷贴治疗后,其中47例痊愈,2例显效,1例有效,总有效率达100%。出现患部色素沉着,毛发脱落40例,出现轻度放射性皮炎6例,出现放射性溃疡4例,经抗感染处理后治愈。B组分次小剂量治疗后,49例痊愈,1例显效,总有效率达100%。出现患部色素沉着,毛发脱落35例,出现轻度放射性皮炎1例,经处理后治愈,其余无不良反应。结论毛细血管瘤是先天性血管病,是婴幼儿的常见良性肿瘤类疾病。90Sr敷贴治疗是一种方法简单,易行,治疗时间短,疗效好,副作用小的治疗方法,对于1岁以下的婴幼儿来说,一次大剂量和分次小剂量治疗在疗效上是无明显差异的,但在副作用上分次小剂量的治疗效果明显优于一次大剂量,所以对于1岁以下的婴幼儿血管瘤患者采用分次小剂量90Sr敷贴治疗是一种治愈率高,副作用小的方法。
Objective Bv different doses of treatment to discuss the best method of treating the illness of haemangioma for the infants with the application treatment of ^90Sr and getting little side-effect. Methods 100 infants who suffered from the illness of strawberry haemangioma and naevus flammeus are cut into two groups. A large number doses of ^90Sr for each of group A for once and small doses for each of group B for several times. Obsering the effect of treatment in two months to make sure whether to have another treatment. Results 47 infants of Group A have got recovery after the application treatment with a large number deses of ^90Sr ： 1 infant has been treated efficiently and 2 have been more efficient. The rate of efficiently is 100%. 40 infants have apparent pigment and their hair have shelled down： 6 have sightly radioactivity dermatitis 4 have radioactivity canker , but got recory after the treatment of inrection. 49 infants of Group B have got recovery after the application treatment with small doses of ^90Sr for several times. The rate of efficiently is 98%. 1 is more efficient. The general rate is 100%. 35 infants have apparent pigment and their hair have shelled down; only 1 has sightly radioactivity dermatitis and he＇s got well after the treatment ： the rest of them have no bad reactions. Conclusions Haemangioma is a congenital blood vessel disease which ordinary appears in infants. It belongs to carcinoid tumour. The application treatment of ^90Sr is a simple method with short curing times and good curative effect, and little side-effect. For the infants younger than one year, there are no abvious differences between a large number doses of ^90Sr for once and small doses for several times. But the latter is bestter than the former on side-effect. So, for the infants who suffer from the illness of haemangioma and younger than one yean the application treatment of ^90Sr with small doses is a high-rate curing method with little side-effect.
出处
《国际医药卫生导报》
2005年第18期100-102,共3页
International Medicine and Health Guidance News
