摘要
目的探讨胰岛素抵抗和中青年脑血管病的关系。方法选取50例年龄小于45岁中青年脑血管病患者(脑梗死39例,脑出血11例),30例健康人作为对照,分别检测血压、血脂、空腹血糖、空腹胰岛素等各项指标。结果空腹血糖和空腹胰岛素明显增高,而胰岛素敏感指数明显降低;收缩压、舒张压、总胆固醇、甘油三脂、低密度脂蛋白、载脂蛋白B、体重指数显著增高(P<0.05),而高密度脂蛋白、载脂蛋白A下降明显(P<0.05)。结论胰岛素抵抗可能是中青年脑血管病的独立危险因素,应加强对易患人群体重、血压、血脂、血糖的防治。
Objective To study the relationship between insulin resistance and cerebral vascular disease of the young and the middle aged people. Methods 50 cases of the young and the middle aged people those age are younger than 45 were chosen. Blood pressure,blood lipid,fasting plasma glucose,fasting serum insulin were measured in cerebral infarction （CI） of 39 cases ,cerebral hemorrhage（CH） of 11 cases and 30 healthy control subjects. Results In the CI group and CH group,FPG,FINS,systolic pressure,diastolic pressure,total cholesterol,triglyceride,low density lipoprotein,apolipoprotein B,weight index were significantly higher than those in the control group （P〈0. 05） ,on the contrary, insulin sensitivity index,high density l ipoprotein,apolipoprotein A ,were significantly lower than those in the control group（P〈0. 05）. Conclusion IR is probably the independent risk factor in cerebral vascular disease of the young and the middle aged people ,and we must prevent and cure blood pressure, blood lipid ,glucose of them.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2005年第4期350-352,共3页
Journal of Apoplexy and Nervous Diseases
关键词
胰岛素抵抗
中青年
脑血管病
Insulin resistance
Cerebral vascular disease
The young and the middle aged people
