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MOC-31在浆膜腔积液转移性腺癌、间皮瘤和增生间皮细胞中表达的检测价值 被引量:3

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摘要 目的探讨检测MOC-31蛋白表达用于鉴别浆膜腔积液转移性腺癌、间皮瘤和增生间皮细胞的价值。方法选用浆膜腔积液标本共93例,其中胸水66例、腹水24例、心包积液3例。经组织学或结合临床资料证实的转移性腺癌55例、恶性上皮型间皮瘤6例、间皮增生32例。每例均制备HE染色的涂片,并用细胞块切片作免疫细胞化学染色。结果MOC-31抗体对转移性腺癌的敏感性为69.1%(38/55),特异性为92.1%(35/38),阳性预测值为92.7%,阴性预测值为67.3%。经χ2检验,MOC-31在腺癌、间皮瘤和增生间皮细胞中的表达差异有统计学意义(χ2=34.1,P<0.005)。结论检测MOC-31蛋白表达有助于鉴别浆膜腔积液转移性腺癌与间皮源性细胞。
出处 《四川大学学报(医学版)》 CAS CSCD 北大核心 2005年第5期734-735,共2页 Journal of Sichuan University(Medical Sciences)
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共引文献19

同被引文献26

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