摘要
目的:比较不同药物用于前列腺电汽化术后镇痛的效果和副反应.方法:80例患者分为4组,布比卡因组(Ⅰ组)用0.125%布比卡因;曲马多组(Ⅱ组)用10 g/L曲马多,吗啡组(Ⅲ组)用0.1 g/L吗啡,芬太尼组(Ⅳ组)用0.005 g/L芬太尼.负荷量均为2 ml,背景剂量均为2 ml/h.术后分别观察视觉模拟评分(VAS)、镇静评分以及血压、心率、呼吸频率、血氧饱和度和恶心呕吐等副反应情况.结果:VAS评分Ⅱ组、Ⅲ组、Ⅳ组近似,Ⅰ组高于其他3组(P<0.01),Ⅱ组镇静评分高于Ⅰ组(P<0.05),其他3组近似(P>0.05);Ⅱ组心率高于其他3组(P<0.01);呼吸频率Ⅰ和Ⅱ组均高于Ⅲ和Ⅳ组(P<0.05～P<0.01).结论:各组病例镇痛效果满意,曲马多、吗啡、芬太尼相对优于布比卡因.
Objective：To compare the clinical effects and adverse effects of different analgesias on patients receiving transurethral electrovaporization of the prostate. Methods： Eighty adult patients were divided into four groups. Group Ⅰ were administered 0. 125 % bupivacaine,group Ⅱ 10 g/L tramadol, group Ⅲ 0.1 g/L morphine and group Ⅳ 0. 005 g/L featanyl. The visual analog scale （VAS） ,analgesia doses,BP, HR,RR,SpO2 and the adverse effects in forms of nausea and vomiting were observed. Results：The VAS of group Ⅰ was the highest among the four groups（P〈0.01）.The tranquilizing score of group Ⅱ was somewhat higher than that of group Ⅰ（ P 〈 0.05）, while it was similar in other three groups （P 〉 0.05）. The incidence of HR in group Ⅰ was higher than that of the other three groups（P 〈 0.01 ） and the incidence of RR was different between each other in all the four groups（ P 〈 0.01）. Conclusions：The analgesia effect in each group is satisfactory,but the effect of group Ⅱ, Ⅲ and Ⅳ is somewhat better than that of group Ⅰ.
出处
《蚌埠医学院学报》
CAS
2005年第5期425-426,共2页
Journal of Bengbu Medical College
